Pyelonephritis XVI. correlates of parasite virulence in acute ascending Escherichia coli pyelonephritis in mice undergoing diuresis.
نویسندگان
چکیده
In a preceding publication (1), a long-term study of ascending pyelonephritis in mice with Escherichia coli strain Yale, confirmed and extended the findings of Keane and Freedman (2). The availability of this model has permitted us to study factors influencing the virulence of E. coli in ascending pyelonephritis. The present paper presents data on 22 strains of E. coli relevant to various factors affecting virulence.
منابع مشابه
Pyelonephritis XV. Long-term study of ascending Escherichia coli pyelonephritis in mice.
Keane and Freedman (1) demonstrated that diuresis produced by feeding 5% glucose rendered mice susceptible to acute ascending pyelonephritis with Escherichia coli. We reported the use of this model in therapeutic studies of E. coli (2) and Proteus mirabilis (3) pyelonephritis. The present investigation, a bacteriologic, immunologic, and pathologic study of long-term infection with E. coli shows...
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Water diuresis has different effects on the outcome of urinary infections in rodents depending on the test organism, the route of inoculation, and the species of animal used. In rats, the production of pyelonephritis following hematogenous inoculation of Staphylococcus aureus, Candida albicans or Streptococcus fecaelis was prevented or cured by water diuresis."' The possible mechanisms by which...
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Recently, water diuresis has been shown to promote chronic Escherichia coli bacteriuria following the injection of bacteria into the bladder lumen of rats with normal urinary systems(l). However, maintenance of bacteriuria for periods up to 56 days has not resulted in renal lesions(l,2). Similar effects of water diuresis on bacteriuria have been observed in mice. In this species, however, sever...
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Systemic and urinary antibody responses were examined in rats with experimental ascending pyelonephritis caused by Escherichia coli O6K13H1. During 12-month follow-up of the infections, bacterial characteristics of the urinary and renal isolates were followed: O and K antigenicity, sensitivity to the bactericidal effect of normal human serum, capacity to attach to urinary tract epithelial cells...
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عنوان ژورنال:
- The Yale Journal of Biology and Medicine
دوره 46 شماره
صفحات -
تاریخ انتشار 1973